The CCMU is a regional hub for research into thematic priorities in critical care. These include sepsis and septic cardiomyopathy, advanced mechanical circulatory support, and application of point-of-care monitoring and diagnostic devices. We coordinate research efforts in the Asia-Pacific region and lead territory-wide observational research in outcomes after intensive care for critical illness.

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Key Positions

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• Steering Committee, COVID-19 Critical Care Consortium

• Lead, Asia-Pacific Extracorporeal Life Support Organization Registry

 

Representative Publications

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1. Ng PY, Chan WSV, Ip A, … Sin WC. (in press). Ten-year territory-wide trends on utilization and clinical outcomes of patients requiring extracorporeal membrane oxygenation in Hong Kong: from 2010 to 2019. Hong Kong Med J.

2. Ng PY, Ma TSK, Ip A, Lee MK, Ng AKY, Ngai CW, Chan WM, Siu CW, Sin WC. Sensitivity of ventricular systolic function to afterload during veno-arterial extracorporeal membrane oxygenation. ESC Heart Fail. 2022 Jul 1. doi: 10.1002/ehf2.13959.

3. Ng PY, Ip A, Fang S, … Sin WC. Effect of hospital case volume on clinical outcomes of patients requiring extracorporeal membrane oxygenation: A territory-wide longitudinal observational study. J Thorac Dis 2022. doi: 10.21037/jtd-21-1512.

4. Ng PY, Li ACC, Fang S, Lin JCR, Ip A, Chan WM, Sin WC, Ngai CW. Predictors of favorable neurological outcomes in a territory-first extracorporeal cardiopulmonary resuscitation program. ASAIO J. 2021 Dec 1. doi: 10.1097/MAT.0000000000001620.

5. Ng PY, Fang S, Ip A, Chan WM, Sin WC, Ngai CW. Changes in patterns of extracorporeal cardiopulmonary resuscitation during the COVID-19 pandemic: an observational study. J Thorac Dis. 2021 Nov;13(11):6499-6501.

6. Sin WC, Ng PY, Ngai WCW, Lai PCK, Mok AYT, Chan RWK. Simulation training for crises during venoarterial extracorporeal membrane oxygenation. J Thorac Dis. 2019 May;11(5):2144-2152.

7. Ng PY, Sin WC, Ng AK, Chan WM. Speckle tracking echocardiography in patients with septic shock: a case control study (SPECKSS). Critical Care. 2016 May 14;20(1):145.

8. Wong, Alfred S. K.; Ma, Tammy S. K.; Chu, Ying Lun Edward; Chan, Ting Bun; Sin, Simon W. C. Buttock Ischemia in Venoarterial Extracorporeal Membrane Oxygenation. A Case Series. . ASAIO Journal: March 11, 2022

9. Alfred Sk Wong, Eva M Marwali , Graeme Maclaren , Mark Ogino , John Fraser , Peter Lai Chi Keung , Liza Fitria , Prieta Adriane , Simon Wc Sin. ECMO simulation training during a worldwide pandemic: The role of ECMO telesimulation. . Perfusion 2022 May 11.  doi: 10.1177/02676591221093868